The Greeks and the Romans used aloe for the treatment of wounds. During the Middle Ages, the yellow liquid in the leaves was used as a laxative. Processed aloe containing aloin is generally used as a laxative, while processed aloe vera juice usually does not contain significant amounts of aloin.
Aloe was also used by Alexander’s army as a healing wound and wound in his long-running campaign in Asia. For the supply of aloe, Alexander conquered Socotra, Yemen, where the warm and dry climate favors its growth.